Pathogen derived resistance and reducing the potential to select viruses with increased virulence

Abstract

Pathogen derived resistance can be used to develop transgenic plants that are resistant to virus infection. It is possible to reduce both potential and perceived risks associated with the transgenes by constructing transgenes that reduce potential for insect transmission and sequence capture. Knowledge of the structural and cellular mechanisms of resistance can lead to the development of a ‘second generation’ of transgenes that have both increased efficacy and greater environmental safely.