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Recent Submissions

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Persistent Illusions: Visual Culture and Historical Memory in Interwar Hungary
Veszprémi, Nóra (Cornell University Press, 2025-06-15)
Persistent Illusions examines the visual representation of history in interwar Hungary, where interpretations of the past were suffused with references to the country's recent territorial loss. In these images of history, nineteenth-century themes and motifs took on new forms to promote twentieth-century political ideas through the new media of modernity. Nóra Veszprémi illustrates how modernization created resilient imagery that persists in cultural memory through a wide range of paintings, prints, stamps, public spectacles, and monuments. In doing so, she challenges the assumption that the official culture of the right-wing, authoritarian regime of Admiral Miklós Horthy was characterized by a superficial revival of historical styles. Instead, she argues that the regime drew on history in complex, modern ways that disseminated motifs and ideological frameworks across political divides. By analyzing how ideology shapes enduring concepts of the past through the evocative power of images, Persistent Illusions encourages the reader to critically examine the legacies of interwar ideas and imagery in the present day.
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Reproducing Revolution: Women's Labor and the War in Kachinland
Hedström, Jenny (Cornell University Press, 2025-06-15)
In Reproducing Revolution, Jenny Hedström explores the Kachin revolution in Myanmar from the perspective of female soldiers, female activists, and women displaced by the violence in northern Myanmar. Hedström argues that the household is an inherently gendered, militarized, and political space that impacts, and is in turn impacted by, the external conflict with which it coexists. In this context, women's everyday labor—the gendered work of childcare, farming, fighting, and forging connections both across households and between the household and the army and the nation—is key to revolutionary survival. Hedström calls this labor militarized social reproduction, and in Reproducing Revolution she demonstrates that such labor is critical to the military effort, and that warfare itself is shaped through everyday domestic action.
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Bridging the Gap Between Joint Commission Accreditation and High-Quality Behavioral Health Care: Reflections on a Survey.
Brody, B.D. (Psychiatry Online, 2025-02-27)
Joint Commission accreditation helps ensure hospital safety and quality. Accreditation also serves as an independent monitor for payers, the public, and other stakeholders. Evidence-based practices necessarily evolve, and ensuring high-quality care requires an ongoing review of which metrics to prioritize. The Joint Commission has recently introduced new voluntary health care equity certification while acknowledging a need to reduce and eliminate unnecessary requirements. In this Open Forum, an inpatient psychiatrist and administrator reflects on the accreditation survey experience and suggests more closely aligning the reimbursement and reputational incentives associated with accreditation with effective, evidence-based interventions.
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Single-cell parallel analysis of DNA damage and transcriptome reveals selective genome vulnerability.
Bai, D.; Cao, Z.; Attada, N.; Song, J.; Zhu, C. (Nature Research, 2025-03-24)
Maintenance of genome integrity is paramount to molecular programs in multicellular organisms. Throughout the lifespan, various endogenous and environmental factors pose persistent threats to the genome, which can result in DNA damage. Understanding the functional consequences of DNA damage requires investigating their preferred genomic distributions and influences on gene regulatory programs. However, such analysis is hindered by both the complex cell-type compositions within organs and the high background levels due to the stochasticity of damage formation. To address these challenges, we developed Paired-Damage-seq for joint analysis of oxidative and single-stranded DNA damage with gene expression in single cells. We applied this approach to cultured HeLa cells and the mouse brain as a proof of concept. Our results indicated the associations between damage formation and epigenetic changes. The distribution of oxidative DNA damage hotspots exhibits cell-type-specific patterns; this selective genome vulnerability, in turn, can predict cell types and dysregulated molecular programs that contribute to disease risks.
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Peripheral Microvascular and Cerebral White Matter Dysfunction in Schizophrenia: Implications of a Body-Brain Endothelial Pathophysiology.
Goldwaser, E.L.; Yuen, A.; Marshall, W.; Adhikari, B.M.; Chiappelli, J.; van der Vaart, A.; Kvarta, M.; Ma, Y.; Du, X.; Gao, S.; Bruce, H.; Donnelly, P.; Mitchell, B.; Hong, C.; Wang, D.J.J.; Kochunov, P.; Hong, L.E. (Oxford University Press, 2025-02-28)
BACKGROUND AND HYPOTHESIS: Schizophrenia spectrum disorder (SSD) is a chronic neuropsychiatric illness accompanied by significant brain structural and functional abnormalities and higher rate of cardio- and cerebrovascular comorbidities. We hypothesized that genetic and environmental risk factors that led to SSD act throughout the body and demonstrated the association between lower integrity of peripheral vascular endothelium and white matter (WM) microstructure. STUDY DESIGN: Microvascular endothelial function was evaluated using brachial artery post-occlusive reactive hyperemia (PORH), in which endothelial responses are measured under reduced blood flow and after blood flow is restored. White matter microstructure was assessed by multi-shell diffusion tensor imaging in n = 48 healthy controls (HCs) and n = 46 SSD. STUDY RESULTS: Patients showed significantly lower PORH (F1,90 = 5.31, P = .02) effect and lower whole-brain fractional anisotropy (FA) values by diffusion imaging (F1,84 = 7.46, P = .008) with a group × post-occlusion time interaction effect (F3,90 = 4.58, P = .02). The PORH and whole-brain FA were significantly correlated in the full sample (r = 0.28, P = .01) and in SSD (r = 0.4, P = .008) separately, but not HC (r = 0.18, P = .28). CONCLUSIONS: This study demonstrated, for the first time, significantly lower integrity of vascular endothelium in participants with SSD and showed that it is associated with WM microstructural abnormalities. Together, these findings support the need for a more holistic, body-brain approach to study the pathophysiology of SSD.