During the trials to produce whey micro-aggregates, it was found that heating 6% whey protein isolates with 0.45% of caseins produced higher yield, and that with pH 5.6 to pH 6.1, the yield ranged from 67% to 76%. Different yield measurement methods were tested and it was found that centrifuging and drying the samples in an oven at 100°C for at least 24 hours produced the most consistent and reliable results. The bench-top trials were successfully scaled up to pilot plant trials as long as the conditions were kept the same. For the concentration of the microaggregates by membrane filtration, good retention and yield were obtained from the pilot plant trials when a 100,000 Molecular Weight Cut-Off Ultrafiltration Spiral Wound Membrane was used, resulting in a 4-fold concentration factor.