Cornell University
Library
Cornell UniversityLibrary

eCommons

Help
Log In(current)
  1. Home
  2. College of Engineering
  3. Biological and Environmental Engineering
  4. BEE 4530 - Computer-Aided Engineering
  5. BEE 4530 - 2002 Student Papers
  6. Albuterol Uptake in Bronchioles

Albuterol Uptake in Bronchioles

Permanent Link(s)
https://hdl.handle.net/1813/202
Collections
BEE 4530 - 2002 Student Papers
Author
Ho, Jeff
Putnam, Lauren
Savath, Vince
Scott, Bill
Abstract

Millions of people around the world suffer from asthma, which is characterized by breathing problems due to constricting bronchioles. While current remedies involve an effective inhaler drug, such as Albuterol, that relieves such symptoms, it still has not been determined exactly how often such a drug should be administered. This project uses GAMBIT and FIDAP to model the uptake of Albuterol in bronchioles in order to determine how often these inhalers should be used to maximize drug delivery and quickly minimize symptoms. A suitable model of drug flow through the bronchioles was developed and we were able to determine how much Albuterol was present in the bronchioles at any given time. It was determined that the concentration reaches steady state at about 0.004 seconds, and concentration at every point was directly proportional to the defined inlet concentration after that. However, since we were not able to find the therapeutic concentration, or the minimum amount of Albuterol needed to be effective in relieving symptoms, we could not quite figure out the proper time spacing between inhaled dosages.

Journal / Series
2002;1
Description
No access to the full paper due to lack of a FERPA release.
Date Issued
2004-11-12T17:21:56Z
Keywords
albuterol
•
bronchioles
•
asthma
Type
term paper

Site Statistics | Help

About eCommons | Policies | Terms of use | Contact Us

copyright © 2002-2026 Cornell University Library | Privacy | Web Accessibility Assistance