This WRI briefing explores the possible presence and transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (COVID-19), in raw (untreated) or partially-treated sewage Note 1. The key question we pose here is: is there scientific evidence to support SARS-CoV-2 transmission and infection through raw or partially-treated sewage? As of January 22, 2021, scientists have shown that the virus has been detected in stool and rectal samples of infected individuals. Consequently, SARS-CoV-2 has been detected in wastewaters all over the world. Multiple studies showed that the virus was viable and/or infectious in stool samples. However, there are no reports of infection through the fecal-oral route to date. Based on our best effort to review the science, there is currently no evidence to suggest infection through contact recreation and professional interaction (sampling, monitoring, etc.). Regardless of the possible risk of exposure to SARS-CoV-2, caution is warranted any time there is possible exposure to untreated wastewater. For stakeholders concerned about the risk of COVID-19 infection associated with their personal and professional activities, and for people handling wastewater or coming in contact with surface water that might reasonably contain raw or partially treated sewage, we refer to existing guidance from public health experts and water professional organizations.