Herbicide resistant tall waterhemp (Amaranthus tuberculatus) continues to be one of the most problematic weeds in US field crops. Thus far, it has primarily established in western and central New York. Our second year of trial results generally followed our first-year results. Herbicides in WSSA groups 2, 5, and 9 should not be relied on for waterhemp control. However, programs that included at least two non-chemical tactics or herbicides from groups 4, 14, 15, 19, or 27 were very effective. Seedbank modelling showed that control at 95%, 98%, or 100% would cause waterhemp emergence to increase, maintain, or decrease over time, respectively. Interseeding annual ryegrass in fields where waterhemp has established is not recommended, but Callisto provided acceptable control of waterhemp while not injuring the annual ryegrass.