Technological breakthroughs in agriculture, including agronomy machinery, high-yield disease-resistant crop varieties and relevant smart informational systems, are crucial to consistently enhance food production and quality. The booming of agriculture-related cultivation techniques, large-scale application of machinery, fertilizers, and genetic engineering technologies contributed to the drastic increases in both crop yields and world population. However, the advancement of agricultural technologies remains imbalanced worldwide, leading to food insecurity in v low- and middle-income countries. The existence of patent barriers and licensing systems can hinder the transfer of imperative technologies to assist agriculture growth in developing countries. With support from The United States Agency for International Development (USAID) Innovation Labs, a comprehensive advisory framework on the management and regulation of the US federally funded agriculture technology projects will be created to guide the organization of these intellectual properties and transferal or dissemination of the intellectual properties (IP) to target users from low- and middle-income countries, seeking to improve food and nutritional security. Using literature review, in-person interviews and online survey, this research paper analyzes diverse categories of IP management and modes of patent transfer to provide insights for regulatory and policy reforms. Finally, this research project hopes that our summary finding, and recommendations can address the vital needs of the low- and middle-income countries and maximize the public benefit.