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Biological Sciences Honors Theses
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Investigations into the impact of and mechanisms behind age-associated impaired healing following peripheral nerve injury
(2020-08)Peripheral nerve injuries (PNI) present a challenging and debilitating problem to both patients and the healthcare industry . Elderly patients in particular demonstrate a significantly reduced rate of recovery after PNI, ... -
Exploring the role of differential gene expression in the age-associated impairment of peripheral nerve regeneration
(2020-06)The peripheral nervous system’s ability to regenerate after injury declines with age, but the reason for why this occurs is unknown. With the goal to understand the role of age-associated transcriptional changes in the ... -
Genetic Basis of Rotenone-induced Parkinson’s Disease Model in Drosophila melanogaster
(2020-06)Parkinson’s disease (PD) is a neurological disorder that exists in sporadic and familial forms and causes the death of dopamine-producing neurons in humans. Rotenone, a pesticide, can be used to induce a model of sporadic ... -
Developing a Tool to Confirm the Successful Differentiation of Human Pluripotent Stem Cells into Cardiomyocytes
(2020-06)Heart disease has been the leading cause of death in the United States since 1921 (Greenlund et al., 2006). However, age-adjusted cardiovascular disease death rates have declined by 55% since 1950, a trend that is in part ... -
Parsing complex community interactions with regulators and non-governmental organizations in relation to local environmental management at Honeoye Lake, New York
(2019-05)This research sought to understand the complex interactions between governmental and non-governmental organizations engaged in assessing or managing the environmental issue of cyanobacterial blooms (commonly known as harmful ... -
Understanding the mechanism of cargo recognition by the Ssh4-Rsp5 ubiquitin ligase complex at the yeast vacuole membrane
(2019-05)The preservation of a healthy proteome is important for all cellular function. Sequential protein quality control (QC) mechanisms along the endocytic pathway safeguard the identity of different organelles by eliminating ... -
A comparison of ovarian morphology and reproductive and metabolic features between South Asian and White women with polycystic ovary syndrome (PCOS)
(2019-05)Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine condition, with known variability in the severity of its cardinal features and long-term health consequences across races and ethnicities. Diagnosis of ... -
Wsb1 and Ksr1 gene add-backs to Chaos3 mammary tumor cells to analyze their role
(2019-05)The RAS protein is crucial in signaling pathways that regulate cellular proliferation. Tumors can form when this normal growth regulation breaks down due to defects in signaling mechanisms. The Chaos3 mouse model has a ... -
Experience and knowledge in Lyme Disease: A scoping review of patient-provider communication
(2019-05)Purpose: Limited research exists on the patient-provider communication dynamic with respect to Lyme disease (LD). There is evidence that being informed, on the part of both patient and provider, enhances communication, ... -
Variation in the uptake of thiamethoxam, a neonicotinoid pesticide, in the NAM Founder inbreds of maize
(2019-05)Neonicotinoid pesticides have recently come under fire for their negative impacts on pollinators. However, seed treatments of neonicotinoid compounds such as imidacloprid are regularly applied to over 79% of maize grown ...
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