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  Approximate Bayesian Computation for Studying Selective Sweep Signatures in Local Coalescence Trees 

  Andrew Marderstein (2017-05)

  Understanding the process of rapid molecular adaptation is important for many key challenges humanity faces today, such as the evolution of pesticide and drug resistance. Our standard population genetic model for describing ...
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  The Role of the Ventral Hippocampus and Anterior Olfactory Nucleus in Contextually Cued Odor Discrimination 

  Joshua Dobbin (2017-05)

  The hippocampus has been shown to play a crucial part in context encoding in rodents. However, the mechanisms by which the hippocampus affects contextually cued behavior have yet to be fully elucidated. In this study, I ...
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  Population Scale Transcriptome Profiling from Mixed Samples using Single-Cell Analysis 

  Destini Gibbs (2017-05)

  One powerfull tool in understanding how genetic variations can lead to changes in gene expression across human population involves measuring mRNA expression levels in large scale, with high-throughput sequencing. Still, ...
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  Mutagenesis of a conserved cysteine in the Hsp70 molecular chaperone BiP: Impact of amino acid substitution on BiP’s ability to protect cells against endoplasmic reticulumderived oxidative stress 

  Xu, Mengni (2015-01)

  Recently, it has been shown that oxidative protein folding in the endoplasmic reticulum (ER) produces potentially significant amounts of cellular reactive oxygen species (ROS). Although ROS accumulation can cause profound ...
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  Diet-induced plasticity in the adult Drosphilia melanogaster midgut 

  Nie, Yunan (2015-05)

  Diet is a foundational factor in metabolism and development. The ratio of dietary macronutrients has significant effects on lifespan and healthspan, and the gut itself has been known to adapt to changes in diet through ...

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