Using enabling technologies, we examine the role geometry, mechanics, and microstructure play in a variety of systems. This includes 3D time-lapse imaging of growing plant roots, confocal elastography of articular cartilage, the use of origami design principles to make mechanical metamaterials, and quantitative image analysis to study the statistical nature of human collective motion at heavy metal concerts. In each case, these projects explore the underlying mechanisms that lead to emergent macroscopic function and form.