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  Mutagenesis of a conserved cysteine in the Hsp70 molecular chaperone BiP: Impact of amino acid substitution on BiP’s ability to protect cells against endoplasmic reticulumderived oxidative stress 

  Xu, Mengni (2015-01)

  Recently, it has been shown that oxidative protein folding in the endoplasmic reticulum (ER) produces potentially significant amounts of cellular reactive oxygen species (ROS). Although ROS accumulation can cause profound ...
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  Diet-induced plasticity in the adult Drosphilia melanogaster midgut 

  Nie, Yunan (2015-05)

  Diet is a foundational factor in metabolism and development. The ratio of dietary macronutrients has significant effects on lifespan and healthspan, and the gut itself has been known to adapt to changes in diet through ...
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  Line tension and bending energy: Understanding the effects on phase separation and the formation of modulated phases 

  Wickramasinghe, Sanjula (2015-05)

  A chemically simple four-component model of animal cell plasma membranes can mimic some important properties of the far more complex biological mixture. In the compositional region of the model mixture where co-existing ...
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  Neuromodulator and olfaction deficits in an MPTP mouse model of Parkinson's Disease 

  Jayakymar, Sachidhanand (2015-01)

  The aim of this project is to quantify the olfactory dysfunctions associated with Parkinson’s Disease in a mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model. Parkinson’s Disease, like many neurodegenerative ...
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  Potential genetic causes for sexual dimorphism in immune response of Drosphila melanogaster in respose to infection with the fungal pathogen Beauberia bassinan 

  Malaret Hernandez, Glen (2015-05)

  The innate immune response is an organism’s first line of defense against disease, be it bacterial, viral, or fungal infection, and it is an integral part of the evolutionary survival of any species. A well-studied model ...

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