Radiofrequency Ablation to kill Kidney Tumors
Sharma, Manish; Lafrance, Tim; Ducharme, Richard; Taylor, Kristin; Wobbrock, Nicholas
Radiofrequency ablation is a technique to destroy tissue cells by heating them above 460C. This method is specifically used in treating tumors smaller than 5 cm in diameter by placing the heated probe within the dysfunctional tissue mass. Depending on the size and shape of the tumor, the ideal time of treatment, voltage, and shape of probe required to eliminate the cells is decided. This study tested a spherical tumor with a 2 cm diameter to determine the best probe shape, voltage, and time of treatment to destroy cancerous cells while keeping surrounding tissue unaffected. Our results indicated that a lower voltage (0.27 volts) and a longer period of time (700 seconds) yielded the best results when using a T-shaped probe. These results account for the diffusion of the heat within the tumor cells while minimizing the damage to the surrounding tissue. Sensitivity analysis indicated that specific heat and tissue density had very small impact on the temperature profile.