Feline cutaneous asthenia is a rare, inherited disorder of collagen production in cats. Similar diseases are found in humans, dogs, mink, horses and mice. In cats, there are two identified modes of inheritance. Both the autosomal dominant and recessive forms cause abnormal packing of Type I collagen. Affected animals have hyperextensible and fragile skin. This disease can be diagnosed via a skin extensibility test, histology and electromicrography. There is no cure, but consistent management can allow affected cats to live long lives.