This thesis explores agricultural practices, market dynamics, and nutritional interventions in Northern Ghana, anchoring on the GROWING project spearheaded by International Potato Center (CIP). It begins by reviewing biofortification, assessing its potential to combat micronutrient deficiencies in the Global South, though the health impacts remain mixed. The research then examines the relationships between rural communities in northern Ghana and traders, highlighting market access, commodity trade, and logistics, with a focus on farmers' experiences with orange-fleshed sweet potato (OFSP). Price trends for key agricultural products across the Northeast, Northern, and Savannah regions are also analysed, revealing significant volatility and challenges in accessing affordable Vitamin A-rich foods. The thesis also presents findings from a Rapid Sweet Potato Trader Survey, emphasizing the role of women in the sweet potato trade and the logistical hurdles they face. Overall, the study provides recommendations to enhance market access, support biofortified crop commercialization, and improve nutritional outcomes in Northern Ghana.