Topics in this Annual Report include: Director's Message (Douglas F. Antczak); Table of Contents; Infectious Diseases and Immunology (Pioneers in Progress: on the forefront of veterinary medicine; Putting Equine Genetics on the Map: the Horse Genome Project; The Future is Now...); Genetics and Development (Unlocking tomorrow's cures...today, Cats suffering from feline leukemia receive boost from Baker researchers, Ahead of the curve: The Baker Institute in the new century); 50 Years of Research and Discovery (Baker Institute had been a powerhouse for the production of academicians...); Degrees Conferred; Baker Institute Faculty and Staff; Sponsor Support; Disbursements in 2000; Partners in Progress: Private support at the Baker Institute; Honoring our four-legged friends: The Baker Institute Memorial Gift Program; In Memory of Dr. Peter V. Poggi, Jr.