Primary vertebral hemangiosarcoma was diagnosed in an adult mixed breed dog. The history, clinical findings, and diagnostic approach for this patient are outlined. Canine hemangiosarcoma, and more specifically, primary vertebral hemangiosarcoma are discussed with regards to incidence, presentation, and treatment options for this disease. Though relatively uncommon, vertebral hemangiosarcoma should be included on the list of differential diagnoses for compressive myelopathies. The long-term prognosis is poor. Although this patient exceeded all expectations for survival, the median survival is likely similar to that of splenic hemangiosarcoma. Treatment can include some combination of surgical decompression, radiation therapy, and doxorubicin chemotherapy. As new treatment modalities become available for the more common locations of hemangiosarcoma, their use can be explored in patients with primary vertebral hemangiosarcoma.