In this work, we employ algebraic techniques and isospectral-type schemes, including similarity, intertwining, gateway, and interweaving relations, to the study of Dyson semigroups and ensembles on the Weyl chamber. (1) First, we construct and provide analytical and ergodic properties of Dyson semigroups, i.e. C0-semigroups on the Weyl chamber. The Weyl chamber is the natural state space to describe the dynamics of eigenvalues of random matrices, as well as for many models in statistical mechanics, population dynamics and combinatorics. (2) Then, motivated by the renormalization group theory developed recently by Patie to study scaling limits and universality of self-adjoint operators, we introduce new discrete scaling operators for studying the local and global scaling limits and universality of determinantal point processes in the discrete Weyl Chambers. These methods extend to the study of non-Markov determinantal Laguerre-Polya semigroups whose invariant distributions are biorthogonal ensembles, including the celebrated Borodin-Muttalib ensembles. (3) Finally, we exploit the concepts of gateway and interweaving relations between continuous and discrete models to design exact algorithms for computing functionals of classical Dyson semigroups.