A three and a half year old female spayed domestic short hair cat presented to a local emergency clinic with a chief complaint of a possible corneal foreign body. However, her clinical picture was pathognomonic for feline corneal sequestrum. Feline corneal sequestrum is reviewed in terms of typical patient presentation, pathogenesis, histology, and treatment options. The case report is used to demonstrate many aspects of feline corneal sequestrum that have been reported in the literature, as well as to explain the rationale behind this patient's treatment, which included lamellar keratectomy, corneoconjunctival transposition, and partial tarsorrphy. In addition, the rational behind the post-operative treatments is explained, including the use of erythromycin ophthalmic ointment, atropine ophthalmic drops, idoxuridine opthalmic drops, and L-lysine.