Crytpococcosis is the most common mycosis of cats worldwide and is most frequently associated with upper respiratory infections, though infection with this organism can result in a number of disease presentations such as cutaneous, ocular, and neurological. A 3 year old female spayed domestic shorthair cat presented to the internal medicine service at Cornell University Hospital for Animals on 5/1/12 with a 3 month history of bilateral nasal discharge, sneezing, and stertor, as well as a 3 day history of bilateral ocular discharge and a 1 week history of pink tissue seen occluding the left nostril, but which regressed after 3 days. A diagnosis was reached by visualization of the yeast in a cytological evaluation of nasal discharge. Clinical signs resolved after several months of treatment with oral fluconazole.