This dataset contains four files containing data from the Florida Fish and Wildlife Conservation Commission shared with the Cornell Wildlife Health Lab (CWHL) at Cornell University for the purpose of the Surveillance Optimization Project for Chronic Wasting Disease (SOP4CWD). Professionals at the source facility have provided written permission for professionals at the CWHL to post this open data to this persistent eCommons repository. FFWCC_WTD_surveillance_2021.csv: This datafile constitutes records in standardized form depicting the results of chronic wasting disease (CWD) testing of white-tailed deer (Odocoileus virginianus) in Florida, US for hunting seasons from 2016-17 to 2020-21, as completed by wildlife health diagnosticians at (or in partnership with) the Florida Fish and Wildlife Conservation Commission. FFWCC_WTD_harvest_2020.csv: This data constitutes the total number of white-tailed deer (Odocoileus virginianus) legally harvested by hunters by county in Florida, US for hunting seasons from 2018-19 to 2019-20, as recorded by the Florida Fish and Wildlife Conservation Commission. FFWCC_processors_2021.csv: This data constitutes the total number wild cervid meat processors and taxidermists by county in Florida, US for the year 2021, as recorded by the Florida Fish and Wildlife Conservation Commission. FFWCC_cervid_facilities_2021.csv: This data constitutes the total number of captive cervid facilities by county in Florida, US for the year 2021, as recorded by the Florida Fish and Wildlife Conservation Commission.