A fourteen-year-old miniature horse mare presented to the Large Animal Clinic at Cornell University on July 10, 2003, with a complaint of anorexia and gait abnormalities over the preceding two days. "Tequila Sunrise" was a previously healthy horse, who had been bred two days earlier and was nursing a two-month-old foal. She was reported to have a decreasing appetite over the past 48 hours, and had begun acting depressed the previous morning. She had developed a stiff gait and relunctance to move over the day, and became ataxic the next. At presentation a thorough physical examination was performed. The horse was noted to be obese, with a body condition score of 5/5. Her temperature, pulses, respiration, perfusion and hydration were normal, but her attitude was severely depressed. Neurologic abnormalities included an inability or severe reluctance to circle in either direction, no menace response bilaterally despite seeming to be visual, and a lack of cutaneous response to pinching with hemostats over the thorax, abdomen, and limbs. All other body system appeared to be normal.