David B. Collum, the Betty R. Miller Professor of Chemistry in the Department of Chemistry and Chemical Biology, describes his unusual entry into chemistry while an undergraduate at Cornell University, a exciting experience in graduate school at Columbia University, and his movement from organic synthesis to physical organometallic chemistry in his early days as an assistant professor at Cornell. The interviewer and former mentor, Professor Bruce Ganem, wander through life at Cornell, the temperament of the department, life as department chairman, and emerging interests in political economics.