As the dairy industry evolves and new strategies are required to improve herd performance, management, and sustainability measures, a potential approach to improve reproductive efficiency, optimize herd management practices, and increase profitability is Targeted Reproductive Management (TRM). Also known as “precision” or “personalized” management, this approach to herd management consists of two keys steps. First, subgroups of cows within a herd that share some biological or performance potential characteristics (predictors) associated with reproduction and performance must be identified ). Second, targeted management strategies specifically designed to optimize cow performance, herd profitability, or alternative metrics of interest are implemented.