In September, 2014, a pastured cow-calf beef cattle herd in central Maine was evaluated for an outbreak of respiratory disease. The herd of 42 animals are rotated together through the same three hillside pastures from approximately April to November. The first affected cow presented with tachypnea, dyspnea and cough in late August. She was treated with ceftiofur and flunixin meglumine, but was found dead two days after presenting with clinical signs. Four weeks later, two additional cows were evaluated for similar evidence of respiratory distress and several other individuals were noted to be coughing. Eighty-two percent of the herd was found to be affected with all age groups represented. Clinical signs included wet intermittent cough, mucopurulent nasal and ocular discharge, harsh lung sounds and fever. This report will describe a herd health approach to respiratory disease diagnosis, treatment and prevention in cattle.