A 10-year old female spayed Labrador Retiever presented to Cornell University’s Hospital for Animals Surgery department for removal of both adrenal glands. The patient was previously diagnosed with adrenal-dependent Hyperadrenocorticism (HAC) at the primary veterinarian, and abdominal ultrasound confirmed the diagnosis by showing bilateral adrenal masses. A ventral midline approach was used to access and remove both adrenal glands with their associated masses, and the patient was immediately started on glucocorticoid and mineralocorticoid replacement therapy in the form of Dexamethasone (0.1mg/kg IV) and Desoxycorticosterone Pivalate (DOCP) (2.2mg/kg IM). Histopathology of the adrenal masses was consistent with adrenocortical carcinoma, which carries a mean survival time of 814 days. The patient was sent home on lifelong medications consisting of oral Prednisone and a monthly intramuscular injection of DOCP.