Immune-mediated thrombocytopenia involves the destruction of platelets via antibody dependant cytotoxicity. It can be a primary autoimmune mediated disease (in which case it is know as Idiopathic Throbocytopenic Purpura or ITP), or it can be induced via a variety of underlying causes including specific drugs, infectious agents, or neoplasms. This study will discuss the history, physical findings, diagnostic workup, treatment, and resolution of one case of ITP in a 3-year-old female spayed Husky mix seen at the Cornell University Hospital for Animals. It will then outline the typical signalment and clinical signs associated with the disease, diagnostic testing, and treatments ranging from emergency therapy to maintenance immunosuppression.