Topics in this Annual Report include: A Message from the Director (Douglas F. Antczak); Staff of the Baker Institute; Perspectives (Advisory Council, Recognitions); Infectious Disease and Immunology (Hadley C. Stephenson Laboratory for the Study of Canine Diseases, Albert C. Bostwick Laboratory for Molecular Biology, Immunology Laboratory, Mucosal Immunity Laboratory, Equine Genetics Center); A Retrospective [Max J. Appel]; Genetics and Development (John M. Olin Laboratory for the Study of Canine Bone and Joint Diseases, Laboratory of Cellular Growth and Differentiation, Laboratory for the Study of Inherited Canine Reproductive Diseases); Beyond the Laboratory (Baker Institute Scientific Conference Series, Honorable Mentions, Publications); Acknowledgments.