A 7-year-old female spayed Beagle hound presented to the emergency service at Cornell University Hospital for Animals for a four day history of severe neck pain and acute onset tetraparesis. Physical exam localized the lesion to the C1-C5 region of the spinal cord, and advanced imaging determined that the lesion was a ruptured disc between vertebrae C5 and C6. The patient was taken to surgery for ventral slot decompression less than 24 hours after presentation, and the disc material was successfully removed from the spinal canal. This paper examines the postoperative care that the patient received, and how a polypharmacy approach paired with physical rehabilitation can work together to increase patient comfort and improve recovery.