This overview report summarises the findings of five case studies on the likely impact of game changing technologies on production and employment in the manufacturing sector in Europe up to 2025: advanced industrial robotics; industrial internet of things; additive manufacturing; electric vehicles; and industrial biotechnology. The adoption of these new technological possibilities will not only have consequences for the production process, but also for the working conditions of those employed on the process and on employment demands at company level. The report highlights the increase in digitisation, the greater demand for highly skilled workers, the expansion of value added to both ends of the product cycle, the even greater importance of data security, the possible reshoring of some production back to Europe, and the need to develop and observe industry standards and protocols.