An eleven year old female spayed Golden Retriever presented for evaluation of rapidly developing oral and skin lesions, as well as a red eye. She was treated by her local veterinarian with antibiotics for potential skin and eye infections, and immediately referred to Cornell. The dog had undergone splenectomy and chemotherapy for hemangiosarcoma six months earlier. Physical exam found two ulcerated cutaneous nodules and multiple erythematous lesions on the oral mucosa. The left nicitans was red, thickened and prolapsed. The remainder of the physical exam was unremarkable. Thoracic radiographs revealed a diffuse nodular pattern. Epitheliotropic lymphoma (T cell) was diagnosed by histopathology of the oral and cutaneous lesions. Initital chemotherapy with the CHOP protocol failed to achieve remission, necessitating change to a rescue protocol (CCNU). The dog?s disease continued to progress and her owners elected euthanasia.