A geriatric, spayed female, German Shepherd Dog with degenerative joint disease affecting multiple joints and comorbidities including hypertrophic cardiomyopathy, urinary incontinence, anxiety and seasonal allergy was evaluated for increased pain in the hips and left elbow. Treatment included bilateral partial hip denervation and extracorporal shockwave therapy (ESWT). Response to treatment was evaluated by force plate analysis and owner assessment. Significant reduction in pain level and improvement in mobility were achieved with the patient presenting for retreatment 16 months after start of initial therapy.