This project investigated the air pollution and health equity impacts of an ongoing transportation planning program in the Tampa area, Tampa Bay Next. Two aspects will be integrated. First, we estimated the changes in pollutant emissions, concentrations, population exposures, and exposure equity that may result from the roadway changes proposed, using a comprehensive modeling system. Second, we performed a qualitative analysis on the health equity impacts of the program from a Health in all Policies decision-making perspective. Results provide a case study for improving air pollution, health, and equity outcomes of large-scale metropolitan transportation infrastructure projects.