The transition period, characterized as the three weeks pre- through three weeks postpartum, is a critical life event for the dairy cow. Around calving, cows involuntarily reduce feed intake; however nutrient demands increase to support fetal growth and milk production. A systemic inflammatory response also occurs at calving which can increase the risk for developing metabolic diseases. For example, the development of fatty liver is a common condition for the transition cow. Milk loss from health incidences particularly in the first 21 days in milk are major contributing factors for economic loss in the dairy industry. Because of these challenges, nutritional strategies are implemented with the goals of improving health and milk production in the transition cow. Methionine (Met) and omega-3 fatty acid (n3 FA) feeding have received attention due to their health benefits.