This seminar presented a case of an adult male great homed owl (Bubo virginianus) which presented to the Janet L. Swanson Wildlife Health Center at Cornell University for assessment of a wing injury. On presentation the patient was determined to have a closed left humeral fracture with the wing distal to the fracture twisted 3 60 degrees. The wing was derotated and the fracture was repaired using an intramedullary pin tied in to an external fixator device. Numerous complications occurred during and after the surgery, presumptively in part due to the extensive soft tissue damage around the fracture site. These complications included two episodes of apparent cardiac anest, self-mutilation to lhe point of removing part of the fixator, continued evidence of pain and anxiety despite multi-modal treatment, and pin site infections. The purpose of this seminar was to briefly review the current literature and knowledge on avian cardiopulmonary resuscitation (CPR) and analgesia.