Jugular thrombosis is a common complication of intravenous catheterization and drug administration in horses. This is because the jugular vein is the most frequently utilized site for venous access in the horse. One study by Gulick and Meager estimated the frequency of jugular thrombosis in horses to be over 50% in horses with intravenous catheters in place for more than 48hrs. Current medical and surgical treatments for jugular thrombosis have varied success rates and do not consistently result in restored blood flow through the jugular vein. Our goal was to create an experimental model of jugular thrombosis in horses by administration of intravenous ferric chloride to achieve an occlusive thrombus that persisted for 30 days. Following thrombus induction, all eight horses showed evidence of thrombophlebitis on physical examination that was confirmed with ultrasound examination and persisted for 30 days.