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  6. Development of a Drug Delivery System with a Constant Rate of Release

Development of a Drug Delivery System with a Constant Rate of Release

File(s)
grp1.doc (1010.5 KB)
Permanent Link(s)
https://hdl.handle.net/1813/2464
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BEE 4530 - 2005 Student Papers
Author
Wheeler, Shannon
Russell, Robert
Leibowitz, Bronna
Price, Corrinne
Cutillo, Monica
Abstract

You do not have to search long to find someone who is taking orally administered medication on a daily basis. Pharmaceuticals such as antibiotics and pain relievers help us live healthier lives; however the administration of these drugs is more involved than simply the swallowing of a pill. Maintaining a constant level of drug in the body is an important requirement for a variety of medications. The more constant the rate of drug release from a pill, the more effective the drug will be. Our model will compare different crater geometries to demonstrate the effect of crater shape on the release rate of a drug under human body conditions. Our objective is to achieve a constant rate of drug release from a pill. Analysis will demonstrate and allow us to conclude that a hemispherical crater geometry is best to accomplish this objective. We were able to achieve a fairly constant rate of release after approximately 17 minutes and this situation would be beneficial for many pharmaceuticals compared to other, less constant drug delivery systems.

Date Issued
2005-11-07T21:17:47Z
Keywords
Diffusivity
•
Naproxen Sodium
•
Pill geometry
•
FIDAP
•
Constant release rate
Type
technical report

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