This news item from Cornell Research is about: Modification-dependent restriction systems (MDRs) in bacteria recognize and cleave modified foreign DNA. These systems are especially important in protecting bacteria against predatory viruses, many of which incorporate modified bases into their DNA to evade detection by other defense systems. If researchers can interfere with the MDRs that halt these bacteriophage viruses, the viruses could be made into a forceful weapon against bacteria that are resistant to common therapies like antibiotics.