In the essay that follows, I will examine three periods in American economic life, with a focus on the interplay of technological innovations, economic transformation, and the responses to them. The first period, focused on the decades between 1870 and1920, experienced the emergence of the corporation as the major form of production and, not surprisingly, the development of oppositional political movements to it. The second period, from 1933 to the 1960s, marked an era of reform efforts to balance the relationship between management and labor, efforts that, ironically, accepted as their premise the structure and rationale of the corporation itself. The third period, from the 1970s to the present, examines on the impact the multinational corporation, operating in a globalized marketplace, on American economic and political life.