Indigenous women are among the most marginalized groups in Mexican society. The intersection of gender with other factors gives rise to the unique forms of discrimination that indigenous women experience. These factors include race, ethnicity, culture, language, religion, socioeconomic status, and education level. The specific experiences of indigenous women call for an intersectional approach to policy making and international human rights law interpretation and application to ensure that indigenous women fully exercise their rights. This thesis analyzes the Convention on the Elimination of all Forms of Discrimination Against Women (CEDAW) with an intersectional perspective to answer three research questions: (1) In what ways can CEDAW be used to hold Mexico accountable for human rights violations against indigenous women in domestic courts? (2) In what ways can CEDAW be used to advance indigenous women's rights at the international level? (3) In what ways can CEDAW be used to inform and transform indigenous peoples' communitarian laws that discriminate against women? The thesis provides an argumentative policy analysis and recommendations to apply CEDAW with an intersectional perspective—in light of the United Nations Declaration on the Rights of Indigenous Peoples, the Indigenous and Tribal Peoples Convention of 1989, and CEDAW Committee's general recommendations and concluding observations—to protect indigenous women's rights at the national, international, and local levels.