After deposition, solution-processed organic materials are susceptible to redissolution by similar solvents. This solvent problem puts undesirable restrictions on the subsequent processing of electronic devices that contain organic materials. In particular, formation of multiple stacked layers is prohibited, as is the patterning of, or on, organic materials. Orthogonal processing utilizes chemically orthogonal fluorinated material systems to resolve these issues and open up previously unattainable processing routes. Four such processes are developed in this work, with one related to stacked devices and three related to patterning organic materials. More specifically, on one hand, a technique is developed to fabricate monolayers of conjugated polymer in stacked OLED devices. On the other hand, fluoropolymers are used to enable patterning of organic materials with otherwise incompatible commercial (organic) photoresists, via roll-to-roll compatible inkjet printing and, finally, for high resolution studies with electron beam lithography.