Arrhythmias in pet rabbits are rarely appreciated in the clinical setting, thus there is a paucity of information in the veterinary literature addressing the topic. This paper will address the diagnosis, treatment options, and prognosis for heart disease in rabbits via the clinical case example of 7 year old intact male Holland lop rabbit who was diagnosed with atrial fibrillation and congestive heart failure secondary to chronic, bilateral, atrioventricular (AV) valve disease. Treatment consisted of positive inotropes, diuretics, vasodilators, and anti-arrhythmic medications. Heart and respiratory rate were closely monitored at home. Periodic rechecks were performed to assess treatment efficacy and renal function.