2026-09-19T23:06:38Zhttps://ecommons.cornell.edu/server/oai/requestoai:ecommons.cornell.edu:1813/1209782026-05-15T17:53:12Zcom_1813_35col_1813_47
Somare, Francisco
Overton, Thomas
Nydam, Daryl
Van Amburgh, Michael
2026-04-02T19:05:13Z
2025-12
ProQuest Submission ID: 12604
ProQuest Publication ID: 32245676
https://hdl.handle.net/1813/120978
https://doi.org/10.7298/ttes-c869
17423292
133 pages
Hypocalcemia during the transition period in dairy cows significantly affects health, reproduction, and milking performance. Although several effective strategies exist to regulate Ca metabolism, the interactions between Ca dynamics, inflammation, and dry matter intake remain poorly understood. This thesis investigates a combination of two commercially validated products; zeolite, a dietary P binding aluminosilicate, and calcidiol, an intermediate vitamin D metabolite. The objectives of our study were to evaluate the effects of the combination of zeolite and calcidiol on mineral metabolism and lactation performance and determine whether this combination is more effective compared to other strategies widely used in dairy farming. In a 2 × 2 factorial experimental design, we investigated the effects of feeding 92 parous close-up dry cows either a negative dietary cation-anion difference diet or a diet with zeolite, with or without calcidiol on milk production and mineral metabolism. Blood samples were collected at select timepoints during the periparturient period. Additionally, daily dry matter intake, milk yield, and rumination, as well as weekly milk composition, body condition scores, and body weights were measured. Data were analyzed using mixed effects models with repeated measures, if applicable, using SAS software. The results indicate that while the combination of zeolite and calcidiol did not improve milk yield in early lactation, zeolite alone significantly increased blood Ca concentrations postpartum.
2026-07-08
en
calcidiol
hypocalcemia
transition cow
zeolite
EFFECTS OF FEEDING A COMBINATION OF SYNTHETIC ZEOLITE A AND 25 HYDROXYVITAMIN D3 DURING THE PREPARTUM PERIOD ON MINERAL METABOLISM AND LACTATION PERFORMANCE OF HOLSTEIN DAIRY COWS
dissertation or thesis
application/pdf
Animal Science
Cornell University
Master of Science
M.S., Animal Science
https://hdl.handle.net/1813/59810.2
Publication
Cornell Theses and Dissertations
Somare, Francisco
5893a6ea-7af3-41d7-abc6-04bcd26ab5df
embargo
embargo
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<Abstract>Hypocalcemia during the transition period in dairy cows significantly affects health, reproduction, and milking performance. Although several effective strategies exist to regulate Ca metabolism, the interactions between Ca dynamics, inflammation, and dry matter intake remain poorly understood. This thesis investigates a combination of two commercially validated products; zeolite, a dietary P binding aluminosilicate, and calcidiol, an intermediate vitamin D metabolite. The objectives of our study were to evaluate the effects of the combination of zeolite and calcidiol on mineral metabolism and lactation performance and determine whether this combination is more effective compared to other strategies widely used in dairy farming. In a 2 × 2 factorial experimental design, we investigated the effects of feeding 92 parous close-up dry cows either a negative dietary cation-anion difference diet or a diet with zeolite, with or without calcidiol on milk production and mineral metabolism. Blood samples were collected at select timepoints during the periparturient period. Additionally, daily dry matter intake, milk yield, and rumination, as well as weekly milk composition, body condition scores, and body weights were measured. Data were analyzed using mixed effects models with repeated measures, if applicable, using SAS software. The results indicate that while the combination of zeolite and calcidiol did not improve milk yield in early lactation, zeolite alone significantly increased blood Ca concentrations postpartum.</Abstract>
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