Bone marrow hypoplasia following fenbendazole administration in an 8 year old dog

dc.contributor.authorBrown, Megan
dc.date.accessioned2011-07-22T18:05:57Z
dc.date.available2011-07-22T18:05:57Z
dc.date.issued2011-02-23
dc.description.abstractAn 8-year-old, male castrated Labrador Retriever presented with coughing, inappetence, lethargy and fever. Two days prior to presentation, one dose of fenbendazole had been given for chronic, intermittent diarrhea. Routine hemogram showed a severe neutropenia and moderate thrombocytopenia, while bone marrow aspirate cytology revealed bone marrow hypoplasia. Supportive care, including fluid therapy initially and broad-spectrum antibiotics for several weeks, resulted in complete resolution of clinical signs and hematologic abnormalities. An adverse drug reaction to fenbendazole was suspected based on the absence of detectable infectious and neoplastic causes as well as resolution of hematologic abnormalities following drug withdrawal.
dc.identifier.urihttps://hdl.handle.net/1813/23351
dc.language.isoen_USen_US
dc.relation.ispartofseriesSenior seminar paper
dc.relation.ispartofseriesSeminar SF610.1 2011
dc.subjectDogs -- Diseases -- Treatment -- Case studiesen_US
dc.subjectDogs -- Effect of drugs on -- Case studies
dc.titleBone marrow hypoplasia following fenbendazole administration in an 8 year old dogen_US
dc.typeterm paperen_US
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