Suspected meningioma in a 7 year old Mixed Breed Dog
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A 7-year old male castrated mixed breed dog presented to the Cornell University Neurology Service in May 2015 for a chief complaint of a left-sided head tilt and five-month history of seizures. On presentation, the patient was quiet, alert, and responsive. Vital signs were within normal parameters. Neurologic examination revealed the following abnormalities: a marked left-sided head tilt, positional vertical nystagmus OU, positional ventral lateral strabismus OS, and marked pain on palpation of the cervical spine and head. An MRI revealed a left-sided, large, mixed intensity, extra-axial, contrast-enhancing mass compressing the brainstem, peri-tumoral edema, and ventriculomegaly with periventricular edema. The patient was treated with phenobarbital, zonisamide, hydroxyurea, prednisone, omeprazole, and pregabalin. At the one month recheck examination, the zonisamide level was found to be below the therapeutic range and was then increased. The patient was weaned off of the phenobarbital due to concerns of excessive sedation. This case report will focus on clinical signs, signalment, and diagnostics as well as treatment therapy, prognosis, classification, and pathology of meningiomas.