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Lymphoma in a 12 year old, female spayed, Airedale Terrier

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A 12 year old, female spayed, Airedale Terrier presented with a history of pollakiuria, hematuria, and inappetence. Based on physical examination and diagnostics the patient was diagnosed with a stage IVa B-cell lymphoma. Lymphoma is the most frequently occurring hematopoietic tumor with an incidence of 13-24 per 100,000.1 Multicentric lymphoma, accounting for approximately 84% of all canine lymphomas, begins as an expansion of neoplastic lymphocytes within the lymph nodes.2 Initial clinical signs include peripheral lymphadenopathy, anorexia or weight loss, or organ specific signs based on neoplastic infiltration. The World Health Organization’s staging and sub-staging is based on lesion distribution determined by the history, clinical signs, and diagnostic tests to allow a systematic assessment of disease extent and correlates with response to treatment. This case report focuses on the diagnosis of B-cell lymphoma in a canine patient. The main topics of discussion include presentation, differential list, diagnostic work-up, long-term management, and chemotherapy side effects.

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2015-04-15

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Lymphadenopathy – Neoplasia – Lymphoma – Multicentric – B cell – Chemotherapy

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case study

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