Acute hepatic necrosis following xylitol ingestion in a 2-year-old dog

dc.contributor.author	Wentworth, Hillary
dc.date.accessioned	2009-10-12T18:25:58Z
dc.date.available	2009-10-12T18:25:58Z
dc.date.issued	2009-10-14
dc.description.abstract	A 2-year-old intact female Cavalier King Charles Spaniel presented to the triage service at the Cornell University Hospital for Animals (CUHA) with a 5-day history of icterus, severe lethargy, anorexia, and vomiting. The patient had a history of eating 2-3 pieces of xylitol-containing chewing gum 8 days before presentation to her referring veterinarian (48 hours before the onset of her clinical signs). Multiple laboratory abnormalities referable to liver damage were observed. Hepatic lymphadenopathy was detected on abdominal ultrasound. A presumptive diagnosis of xylitol toxicosis was made based on the patient's history and laboratory findings. Supportive and hepatoprotective therapy was instituted and the patient recovered after a treatment course of several weeks. Principals of the pathogenesis, diagnosis, treatment, and prognosis of canine xylitol toxicosis are discussed.
dc.identifier.uri	https://hdl.handle.net/1813/13801
dc.language.iso	en_US	en_US
dc.relation.ispartofseries	Senior seminar paper
dc.relation.ispartofseries	Seminar SF610.1 2010
dc.subject	Dogs -- Effect of chemicals on -- Case studies	en_US
dc.subject	Dogs -- Toxicology -- Case studies
dc.title	Acute hepatic necrosis following xylitol ingestion in a 2-year-old dog	en_US
dc.type	term paper	en_US

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