Henry, a 12 year old MC Border Collie mix, presented for evaluation of right unilateral nasal stertor and decreased air flow. CT imaging, rhinoscopy, and histopathology were consistent with chronic inflammation. No underlying etiology was determined and he was treated empirically with anti-parasitics, steroids, and antibiotics. There was no response to treatment, and his nasal disease progressed to unilateral epistaxis and facial deformity in the following 6 months. CT imaging was repeated, and now there was a right-sided soft-tissue opacity mass causing significant lysis of the turbinates, maxilla, and cribriform plate. Histopathology was consistent with nasal adenocarcinoma. Metastasis to the right mandibular lymph node was identified during clinical staging. Henry was treated with a palliative course of megavoltage radiation (20 Gy) and maintained a good quality of life following treatment.