eCommons

 

Exploring the Impact of Glycerol Monolaurate in Gut Health: A Review of In Vivo Studies

Other Titles

Abstract

Glycerol monolaurate (GML), a naturally occurring medium-chain monoglyceride, has attracted increasingly interest due to its special antivirus ability and potential benefits on gut health. This review focuses on animal research to explore how GML supplementation impacts intestinal morphology, gut microbiota composition, and immune function. Studies show that GML could enhance the structure of the villus, which may in turn lead to better nutrient absorption. GML has been shown to resemble properties of prebiotics due to its ability to regulate microbial diversity of the intestines for favorable microbiota such as Barnesiella or Bacteroides and to enhance production of short chain fatty acids. The results have shown that GML exhibits anti-inflammatory activities through its capacity to lower pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-α, increase anti-inflammatory cytokines like IL-10 and TGF-β1, and enhance expressions of tight junction proteins.

Journal / Series

Volume & Issue

Description

Sponsorship

Date Issued

2024

Publisher

Keywords

Location

Effective Date

Expiration Date

Sector

Employer

Union

Union Local

NAICS

Number of Workers

Committee Chair

Tako, Elad

Committee Co-Chair

Committee Member

Degree Discipline

Degree Name

Degree Level

Related Version

Related DOI

Related To

Related Part

Based on Related Item

Has Other Format(s)

Part of Related Item

Related To

Related Publication(s)

Link(s) to Related Publication(s)

References

Link(s) to Reference(s)

Previously Published As

Government Document

ISBN

ISMN

ISSN

Other Identifiers

Rights

Attribution 4.0 International

Types

dissertation or thesis

Accessibility Feature

Accessibility Hazard

Accessibility Summary

Link(s) to Catalog Record