Alex Poe is a 15-year old mixed breed canine with a year and a half history of bilateral refractory corneal erosion and opacity. Diseases leading to refractory canine corneal erosion are frustrating to handle in a clinical situation unless an appropriate pathologic diagnosis is made. Primary causes of corneal erosion include persistent mechanical irritation, primary corneal epithelial disease, or primary corneal endothelial disease. Conventional therapies for corneal epithelial and corneal endothelial diseases have differed only in the administration of hyperosmotic agents in cases of primary endothelial disease. However, historically primary endothelial disease patients have remained refractory to therapy due to the inability to control corneal edema leading to bullous keratopathy and persistent ulceration. The use of a cautery probe to perform thermokeratoplasty on the cornea has been used in human patients in the past and has shown promise in treating canine corneal endothelial disease.