Polyostotic T-lymphoblastic Leukemia/Lymphoma in an 11-month-old Great Dane

dc.contributor.author	Park, Steph
dc.date.accessioned	2019-06-12T18:38:39Z
dc.date.available	2019-06-12T18:38:39Z
dc.date.issued	2016-09-28
dc.description.abstract	An 11-month-old, intact female Great Dane presented to the Cornell Emergency Service for a one-week history of non-weight-bearing lameness of her right hindlimb. Radiographs from the primary veterinarian identified aggressive bone lesions of the right femoral metaphyses. She was transferred to the Orthopedics Service for diagnostic workup; bloodwork revealed polycythemia, azotemia, and severe hypercalcemia. A CT scan revealed erosive lesions affecting both femurs and left scapula, a soft tissue mass caudal to the right stifle, and a mediastinal soft tissue mass. Smear evaluation of aspirates from the stifle mass returned with high suspicion of lymphoma. She declined clinically despite supportive care in hospital, and the owners elected euthanasia. The patient was submitted for necropsy, which made an initial gross morphologic diagnosis of metastatic thymic lymphoma. Further histopathological examination and immunohistochemistry led to a revision of this initial diagnosis to one of T lymphoblastic leukemia/lymphoma.	en_US
dc.identifier.uri	https://hdl.handle.net/1813/66386
dc.language.iso	en_US	en_US
dc.subject	lymphoma, leukemia, T-lymphoblastic, polyostotic, neoplasia	en_US
dc.title	Polyostotic T-lymphoblastic Leukemia/Lymphoma in an 11-month-old Great Dane	en_US
dc.type	case study	en_US

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