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Data and Scripts from: Competitive social feedback amplifies the role of early life contingency in male mice

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Abstract

These files contain data supporting all results reported in Zipple et al. Competitive social feedback amplifies the role of early life contingency in male mice. Contingency (or ‘luck’) in early life plays an important role in shaping individuals’ development. Here we show that competition magnifies early contingency by comparing the developmental trajectories of functionally genetically identical, free-living mice who either experienced high levels of resource competition (males) or did not (females). Male resource competition results in a feedback loop that magnifies the importance of early contingency and pushes individuals onto divergent, self-reinforcing life trajectories, while the same process appears absent in females. Our results indicate that the strength of sexual selection may be self-limiting and highlight the potential for contingency to lead to differences in life outcomes, even in the absence of any underlying differences in ability (‘merit’).

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Please cite as: Matthew N. Zipple, Daniel Chang Kuo, Xinmiao Meng, Tess M. Reichard, Kwynn Guess, Caleb C. Vogt, Andrew H. Moeller, Michael J. Sheehan. (2024) Data and Scripts from: Competitive social feedback amplifies the role of early life contingency in male mice. [Dataset] Cornell University eCommons Repository. https://doi.org/10.7298/qcpe-9h62

Sponsorship

We gratefully acknowledge our sources of funding that made this work possible. MNZ has been supported by an NSF postdoctoral fellowship in biology (award # 2109636) and a Klarman postdoctoral research fellowship from Cornell University. CCV is supported by a Mong Neurotechnology Fellowship from Cornell University. This work was also supported by Pilot and Feasibility awards to MNZ and MJS from the Animal Models for the Social Dimensions of Health and Aging Network (project #5R24AG065172-03). The costs of care for the mouse colony were supported in part by R35 GM138284 to Andrew Moeller.

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2024

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Individuality; Social Behavior; Mus musculus; Inequality

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Zipple, M. N., Chang Kuo, D., Meng, X., Reichard, T. M., Guess, K., Vogt, C. C., Moeller, A. H., & Sheehan, M. J. (2025). Competitive social feedback amplifies the role of early life contingency in male mice. Science, 387(6729), 81–85. https://doi.org/10.1126/science.adq0579

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CC0 1.0 Universal

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